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Injectable Probes Could Transform Brain Monitoring

Conductive polymer mesh could be a boon to brain research


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To solve the mysteries of the brain, scientists need to delicately, precisely monitor neurons in living subjects. Brain probes, however, have generally been brute-force instruments. A team at Harvard University led by chemist Charles Lieber hopes that silky soft polymer mesh implants will change this situation. So far the researchers have tested the mesh, which is embedded with electronic sensors, in living mice. Once it has been proved safe, it could be used in people to study how cognition arises from the action of individual neurons and to treat diseases such as Parkinson's.

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Illustration by Don Foley

Seth Fletcher is chief features editor at Scientific American. His book Einstein's Shadow (Ecco, 2018), on the Event Horizon Telescope and the quest to take the first picture of a black hole, was excerpted in the New York Times Magazine and named a New York Times Book Review Editor's Choice. His book Bottled Lightning (2011) was the first definitive account of the invention of the lithium-ion battery and the 21st century rebirth of the electric car. His writing has appeared in the New York Times Magazine, the New York Times op-ed page, Popular Science, Fortune, Men's Journal, Outside and other publications. His television and radio appearances have included CBS's Face the Nation, NPR's Fresh Air, the BBC World Service, and NPR's Morning Edition, Science Friday, Marketplace and The Takeaway. He has a master's degree from the Missouri School of Journalism and bachelor's degrees in English and philosophy from the University of Missouri.

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Scientific American Magazine Vol 313 Issue 6This article was originally published with the title “Soft, Injectable Electronic Probes for the Brain” in Scientific American Magazine Vol. 313 No. 6 (), p. 34
doi:10.1038/scientificamerican1215-34b